由孕甾双烯醇酮醋酸酯制黄体酮的催化氢化,国内外均采用雷尼镍催化剂,目前国内生产黄体酮的总产率仅62.4%。若将雷尼镍改为钯/炭催化剂,氧化产率达到96%。如果水解产率按最低的95%、氧化产率以80%计算,则黄体酮的总产率达到72%以卜。说明:改用钯/炭(Pd/C)催化剂生产是有竞争力的,对于原料的充分利用,提高产物的产率以及降低产品成本是有希望的。 By progesterone ketones acetate progesterone catalytic hydrogenation, both at home and abroad are used Raney nickel catalyst, the current domestic production of progesterone total yield of only 62.4%. If the Raney nickel to palladium / carbon catalyst, the oxidation yield reached 96%. If the hydrolysis yield is the lowest 95%, the oxidation yield is 80%, the total progesterone yield is 72%. Note: The switch to palladium / carbon (Pd / C) catalyst production is competitive, for the full utilization of raw materials, improve product yield and reduce product costs are promising.