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1977年-1986年的10年间,日本秋田大学医学部内科住院的242例造血系统肿瘤病人中,白血病129例,包括急性白血病100例,红白血病8例,慢性白血病21例。恶性淋巴瘤84例,包括何杰金氏病7例,非何杰金氏病71例,ATL 2例,恶性组织细胞病4例。多发性骨髓瘤29例,包括浆细胞性白血病2例。观察其血清钠、钾、钙、磷,血清肌酐,尿蛋白、糖、管型的检查结果。对其一般临床资料,如发热、尿量、治疗情况进行了调查。对死亡的131例中的107例进行了尸解,肾病理学检查。分析结果发现,80.1%的病例有电解质异常。按疾病计,最多见于骨髓瘤,达85.7%,其次为白血病,为82%,恶性淋巴瘤为74.5%,以血清肌酐大于1.5mg/dl为肾功能损害的指标,白血病为27.4%,恶性淋巴瘤为21.8%,骨髓瘤为42.9%,全体计为
From 1977 to 1986, 129 leukemia patients, including 100 acute leukemia, 8 erythroleukemia and 21 chronic leukemia, were enrolled in 242 patients with hematopoietic tumor who were hospitalized in Department of Medicine, Akita University. 84 cases of malignant lymphoma, including 7 cases of Hodgkin’s disease, 71 cases of non-Hodgkin’s disease, 2 cases of ATL, 4 cases of malignant histiocytosis. 29 cases of multiple myeloma, including plasma cell leukemia in 2 cases. Observe the serum sodium, potassium, calcium, phosphorus, serum creatinine, urine protein, sugar, tube type test results. The general clinical data, such as fever, urine output, treatment were investigated. Of the 131 deaths, 107 were examined by autopsy and nephrology. The analysis found that 80.1% of the cases had electrolyte abnormalities. By disease, the most common in myeloma, up to 85.7%, followed by leukemia, 82%, 74.5% of malignant lymphoma, serum creatinine greater than 1.5mg / dl as indicators of renal dysfunction, leukemia was 27.4%, malignant lymphoma Tumors were 21.8%, myeloma 42.9%, all as