本文收集17－41周胎儿标本50例，测量了不同孕月胎儿的阑尾长度和横径，经HE染色，观察阑尾壁的结构，利用免疫组织化学方法，观察了阑尾粘膜内嗜铬粒A（CGA）的免疫阳性细胞，并与回肠末端和盲肠的阳性细胞进行了比较，说明CGA细胞的密度由回肠、盲肠、阑尾依次减少，同时表明胎龄21周至41周间CGA密度无明显变化；淋巴组织增生较明显。 In this study, we collected 50 fetuses from 17 to 41 weeks and measured appendix length and transverse diameter of fetus at different gestational months. By HE staining, the structure of the appendix was observed. Immunohistochemistry was used to observe the changes of chromogranin A CGA) immunoreactive cells, and compared with the terminal ileum and cecum positive cells, indicating that the density of CGA cells from the ileum, cecum, appendix in turn decreased, while gestational age 21 to 41 weeks showed no significant change in CGA density; lymph Tissue proliferation more obvious.