论文部分内容阅读
从19世纪末以来,阿司匹林(Yixians Huizangsuan)作为一种非甾体抗炎镇痛剂广泛应用于解热、镇痛、消炎。通常,阿斯匹林一直是以口服给药,因此消化道溃疡、出血等胃肠道副反应就成为一个难以解决的问题。日本绿十字株式会社进行广泛的研究,利用阿司匹林的DL-赖氨酸盐(乙酰水杨酸-DL-赖氨酸),发展了较稳定的静脉注射用阿司匹林针剂—威诺匹林。以静注方法使用阿司匹林,不仅能避免口服引起的胃肠道反应,还可迅速地提高阿司匹林在血中的浓度。动物实验证明,静注阿司匹林见效快,其消炎、镇痛及退热作用与口服阿司匹林相
Since the late 19th century, aspirin (Yixians Huizangsuan) as a non-steroidal anti-inflammatory analgesic is widely used in antipyretic, analgesic, anti-inflammatory. In general, aspirin has been administered orally, so gastrointestinal side effects such as peptic ulcer and bleeding have become an unmanageable problem. Japan Green Cross has conducted extensive research to develop a more stable intravenous injection of aspirin, aspirin DL-lysine (acetylsalicylic acid-DL-lysine). The use of aspirin intravenously not only avoids oral gastrointestinal reactions, but also rapidly increases the concentration of aspirin in the blood. Animal experiments show that intravenous aspirin quick, anti-inflammatory, analgesic and antipyretic effects and oral aspirin phase