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假肉瘤型鳞状细胞癌,又名“梭形细胞癌”,属鳞癌的特殊亚型,是近年文献中争论较多的一类肿瘤。以往曾认为是“癌肉瘤”(肉瘤部分主要为纤维肉瘤)。通过电镜研究,对其本质的看法渐趋一致:肉瘤样细胞与鳞癌细胞并非二元性来源,前者系从后者转化而来,获得了产生胶原纤维的能力,却仍保留鳞状细胞的部分超微结构特征。这种兼有两者特性的瘤细胞有人称之为细胞的“杂交种”,这种现象被称为“上皮的间充质性化生”。还有些病例可部分向破骨细胞、骨或软骨性方向分化。目前国外文献中大多称为“假性肉瘤”、“肉瘤样癌”、“化生性癌”及“梭形细胞癌”。我们认为,
Pseudosarcoma-type squamous cell carcinoma, also known as “spindle cell carcinoma,” is a special subtype of squamous cell carcinoma. It is a type of tumor that has been controversial in the literature in recent years. In the past, it was considered to be a “carcinoma” (sarcoma is mainly a fibrosarcoma). Through electron microscopy, the nature of its observations gradually converge: sarcomatoid cells and squamous cell carcinoma cells are not dual sources of transformation. The former is transformed from the latter and acquires the ability to produce collagen fibers while retaining squamous cells. Part of the ultrastructure features. This type of tumor cell with both properties is called a “hybrid” cell, and this phenomenon is called “epithelial mesenchymal metaplasia.” In some cases, some cases may differentiate into osteoclasts, bones, or cartilage. At present, foreign literature is mostly called “pseudosarcoma”, “sarcomatoid carcinoma”, “metastatic carcinoma” and “fusiform cell carcinoma.” We believe,