助孕药物的使用能引起卵巢癌的高发。目前意大利进行了大量的多中心研究。 方法 资料取自意大利4个区自1992年1月～1999年9月间患卵巢癌的病例研究。病例组共1031例妇女,平均年龄56(18～79)岁,医院确诊为卵巢癌的患者,不包括边缘性肿瘤。对照组2411例妇女,平均年龄57(17～79)岁,同地区的 The use of fertility drugs can cause high incidence of ovarian cancer. At present, a large number of multicentre studies have been conducted in Italy. Methods Data were collected from four Italian patients with ovarian cancer from January 1992 to September 1999. A total of 1031 women in the case group, mean age 56 (18 to 79 years), were diagnosed with ovarian cancer in the hospital, excluding marginal tumors. The control group of 2411 women, the average age of 57 (17 ~ 79) years of age, with the same area