从免疫宿主的淋巴样细胞中提取的免疫核糖核酸(iRNA)能在体内外传递特异的免疫反应,使正常淋巴细胞转变为对特异抗原起反应的效应细胞,这已被广泛证实。但是有关 iRNA 的作用机制目前还不十分清楚,至于测定经 iRNA 致敏后淋巴细胞内 cAMP和 cGMP 水平变化情况,目前尚未见有报道。本实验使用异种动物 iRNA 致敏小鼠脾淋巴细胞,然后再测定致敏淋巴细胞内 It has been widely confirmed that immune RNA (iRNA) extracted from the lymphoid cells of the immunized host can transfer specific immune responses in vitro and in vivo, and normal lymphocytes can be converted into effector cells that respond to specific antigens. However, the mechanism of action of iRNA is still unclear. As for the determination of cAMP and cGMP levels in lymphocytes after sensitization with iRNA, it has not yet been reported. In this experiment, xenogeneic iRNA was used to sensitize mouse splenic lymphocytes and then to measure sensitized lymphocytes.