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目的通过临床资料分析,探讨垂体腺瘤对男性性功能的影响。方法通过2013年5月至2015年3月我院收治的160例男性垂体腺瘤患者的临床资料,从垂体腺瘤大小、病理分型、肿瘤侵蚀性和血清睾酮水平对性功能的影响进行分析。结果垂体微腺瘤术后性功能障碍(SD)恢复正常率100%,大腺瘤患者性功能障碍恢复正常率31.7%,巨大腺瘤患者性功能障碍恢复正常率20.5%,三组组间比较差异有统计学意义(P<0.05);肿瘤是否侵蚀性与术后性功能恢复无关(P>0.05)。功能性垂体腺瘤患者术前SD发生率与术后SD残留率比较差异无统计学意义(P>0.05),而无功能性垂体腺瘤患者术前SD发生率与术后SD残留率比较差异有统计学意义(P<0.05)。垂体腺瘤患者术后血睾酮水平与SD改善有关(P<0.05)。结论垂体腺瘤的体积大小、病理类型成为垂体腺瘤患者SD的影响因素,血清睾酮水平即是衡量患者术后性功能恢复情况的重要指标。
Objective To investigate the effect of pituitary adenoma on male sexual function through clinical data analysis. Methods The clinical data of 160 male patients with pituitary adenoma who were admitted to our hospital from May 2013 to March 2015 were analyzed in terms of the size, pathological type, tumor aggressiveness and serum testosterone level . Results The recovery rate of sexual dysfunction (SD) of pituitary microadenomas was 100%, the recovery rate of sexual dysfunction in patients with large adenoma was 31.7%, and the recovery rate of sexual dysfunction in patients with giant adenoma was 20.5%. Comparing the three groups The difference was statistically significant (P <0.05). The erosiveness of the tumor had no correlation with postoperative sexual function recovery (P> 0.05). There was no significant difference between preoperative SD rate and postoperative SD residual rate in patients with functional pituitary adenoma (P> 0.05), while there was no significant difference between preoperative SD rate and postoperative SD residual rate in patients with functional pituitary adenoma There was statistical significance (P <0.05). Postoperative serum testosterone levels in patients with pituitary adenoma correlate with improvement of SD (P <0.05). Conclusion The size and pathological type of pituitary adenomas are the influencing factors of SD in patients with pituitary adenoma. Serum testosterone level is an important index to measure the postoperative recovery of sexual function.