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目的判断葡萄胎患者的预后状况。方法观察葡萄胎患者刮宫后：①阴道流血及血HCG变化情况；②葡萄胎组织颗粒大小、子宫肌壁间有无浸润病灶及滋养细胞增生程度。结果发现葡萄胎患者二次刮宫后：①阴道不规则流血超过2周者，血HCG8周内仍未降至正常者；②葡萄组织以小葡萄为主、子宫肌壁间浸润病灶超过2周者，其恶变率明显增高。结论①观察患者血HCG水平及子宫肌壁间有无浸润病灶是首要监测手段。②对以小葡萄为主且二次刮宫后不规则阴道流血超过2周者应高度重视。③二次刮宫后血HCG8周内仍未降至正常、子宫肌壁间病灶持续存在，结合其临床表现，如伴有不规则阴道流血者应视其恶变。
Objective To determine the prognosis of hydatidiform mole patients. Methods After the curettage of patients with hydatidiform mole: ① vaginal bleeding and blood HCG changes; ② hydatidiform mole size, presence or absence of infiltration of uterine muscle wall and trophoblast hyperplasia. The results showed that after the second curettage in patients with hydatidiform moles: ① vaginal irregular bloodshed more than 2 weeks, blood HCG 8 weeks did not fall to normal; ② grapes mainly grape, infiltration of the uterine muscle wall more than 2 weeks , The malignant transformation rate was significantly higher. Conclusion ① Observe the level of HCG in patients with uterine muscle wall and whether invasive lesions is the primary means of monitoring. ② to the main grape and after the second curettage irregular vaginal bleeding more than 2 weeks should be highly valued. ③ secondary curettage HCG8 weeks after the blood has not yet dropped to normal, uterine muscular wall lesions persist, combined with its clinical manifestations, such as with irregular vaginal bleeding should be treated as malignant.