沙眼所致失明已引起全世界的关注，而反复涂四环素眼膏治疗活动性沙眼又有很多缺点。已知单次口服新的azalide类抗生素azithromcin治疗生殖器沙眼衣原体感染有效，因此，作者研究该药治疗沙眼的效果。作者在冈比亚（非洲）二个流行沙眼的村庄进行随机、单盲比较研究，实验组口 Trachoma caused by blindness has attracted worldwide attention, and repeatedly coated tetracycline eye ointment for the treatment of active trachoma have many shortcomings. It is known that a single oral administration of azithromcin, an azalide antibiotic, is effective in treating genital C. trachomatis infection. Therefore, the authors investigated the effect of this drug in the treatment of trachoma. The authors conducted a randomized, single-blind comparative study in two endemic trachoma villages in the Gambia (Africa). The experimental group