论文部分内容阅读
自蛇毒（ＤｕｃｈｅｓｎｅａｉｎｄｉｃａＦｏｃｋ）全草中分离出６个化合物，其中，２个为新化合物，分别命名为蛇莓甙Ａ（ｄｕｃｈｅｓｉｄｅＡ）和蛇莓甙Ｂ（ｄｕｃｈｅｓｉｄｅＢ），经化学及光谱（ＵＶ，１Ｒ，１ＨＮＭＲ，１３ＣＮＭＲ，ＮＯＥＤＳ和ＭＳ）分析确定，蛇莓甙Ａ的结构为３＇－Ｏ－甲基－鞣花酸－４－Ｏ－β－Ｄ－吡喃木糖甙（Ⅰ），蛇莓甙Ｂ的结构为３＇－Ｏ－甲基－鞣花酸－４－Ｏ－α－Ｌ－呋喃阿拉伯糖甙（Ⅱ）。另外４个化合物为已知三萜类化合物：３β－羟基－乌苏烷－１２－烯－２８－羧酸（Ⅲ），２α，３β，１９α－三羟基－乌苏烷－１２－烯－２８－羧酸（Ⅳ），２α，３β，１９α－三羟基－乌苏烷－１２－烯－２８－羧酸－２８－Ｏ－β－Ｄ－吡喃葡萄糖甙（Ⅴ），２α，３α，１９α－三羟基－乌苏烷－１２－烯－２８－羧酸－２８－Ｏ－β－Ｄ－吡喃葡萄糖甙（Ⅵ）。其中化合物Ⅳ，Ⅴ和Ⅵ为首次从该属植物中分离得到。
Six compounds were isolated from the whole plant of Duchesneaindica Rock, of which two were new compounds, named duchesideA and duchesideB respectively. Their chemical and spectral properties (UV, 1R, 1H NMR, 13CNMR, NOEDS and MS) showed that the structure of snake berry glycosides A was 3’-O-methyl-ellagic acid-4-O-β-D-xylopyranoside (Ⅰ) The structure of B is 3’-O-methyl-ellagic acid-4-O-α-L-arabinopyranoside (Ⅱ). The other four compounds are known triterpenes: 3β-hydroxy-ursu-12-ene-28-carboxylic acid (Ⅲ), 2α, 3β, 19α-trihydroxy-urasadin-12-ene-28 (Ⅳ), 2α, 3β, 19α-trihydroxy-ursane-12-ene-28-carboxylic acid-28-O-β-D-glucopyranoside (V) - trihydroxy-sulphone-12-ene-28-carboxylic acid-28-O-β-D-glucopyranoside (Ⅵ). The compounds Ⅳ, Ⅴ and Ⅵ were isolated from this genus for the first time.