钙是心脏最重要的离子调节器之一,在心脏收缩-舒张过程中起着重要的作用。肌纤维膜中存在着2种维持Ca2+浓度到恒定水平的机制,即钠/钙交换器和肌纤维膜钙泵,相对钠/钙交换器而言,肌纤维膜钙泵从心肌排出钙较少,因此,长期以来肌纤维膜钙泵的作用被认为是维持舒张期低钙水平。近年来,肌纤维膜钙泵的研究显示肌纤维膜钙泵在心血管系统的信号转导中可能起着重要的作用。 Calcium is one of the most important ion regulators in the heart and plays an important role in systole-diastolic processes. There are two kinds of muscle fiber membrane to maintain the concentration of Ca2 to a constant level of mechanism, that is, sodium / calcium exchanger and muscle fiber membrane calcium pump, relative to the sodium / calcium exchanger, the muscle fiber membrane calcium pump less calcium from the myocardium, The long-term role of muscle fiber membrane calcium pump is considered to maintain diastolic low calcium levels. In recent years, the study of muscle fiber membrane calcium pump shows that muscle fiber membrane calcium pump may play an important role in the signal transduction of cardiovascular system.