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目的对阿奇霉素治疗非淋菌性尿道炎的临床疗效进行研究。方法选择2010年5月至2012年3月临床确诊的359例非淋菌性尿道炎的患者进行研究,随机分为两组,一组采用阿奇霉素治疗,一组采用盐酸多西环素治疗。结果阿奇霉素治疗组治愈率76.8%,有效率95.0%,多西环素治疗组治愈率60.1%,有效率87.6%。治愈率和有效率两组相比差异有统计学意义(P<0.05)。两组不良反应相比,阿奇霉素治疗组相对较少,两组相比差异有统计学意义(P<0.05)。结论阿奇霉素治疗非淋菌性尿道炎临床效果较好,不良反应少,值得临床推广应用。
Objective To study the clinical efficacy of azithromycin in the treatment of non-gonococcal urethritis. Methods 359 patients with non-gonococcal urethritis diagnosed from May 2010 to March 2012 were randomly divided into two groups. One group was treated with azithromycin and the other group was treated with doxycycline hydrochloride. Results The cure rate of azithromycin treatment group was 76.8%, the effective rate was 95.0%. The cure rate of doxycycline group was 60.1% and the effective rate was 87.6%. There was significant difference between cure rate and effective rate (P <0.05). Compared with the two groups, azithromycin treatment group was relatively small, the difference between the two groups was statistically significant (P <0.05). Conclusion Azithromycin has a better clinical effect and less adverse reactions in non-gonococcal urethritis, which is worthy of clinical application.