急性胰腺炎是消化系统常见疾病,而重症胰腺炎病情凶险,病死率一直居高不下,但其发病机制仍未完全阐明。目前,有“炎症瀑布”、“二次打击”、“白细胞过度激活”、“胰腺微循环障碍”等学说,这些学说的建立,都与白细胞血管外迁移和聚集密切相关。而白细胞的迁移和聚集依赖于炎 Acute pancreatitis is a common disease of the digestive system, while the severity of severe pancreatitis is dangerous, the case fatality rate has been high, but its pathogenesis has not been fully elucidated. At present, there are such theories as “inflammatory waterfall”, “second strike”, “excessive activation of leucocytes” and “pancreatic microcirculation disorder”. All these theories are closely related to extravascular migration and aggregation of leukocytes. Leukocyte migration and aggregation, however, depend on inflammation