睑痉挛、口和下颌肌张力障碍综合征(Meige’s syndrome)是少见疾病,现将我们遇到的2例报告如下: 例1,张△△,女,34岁,会计。因视物模糊半年,睁眼困难4月入院。病员于入院前半年无明显诱因出现视物模糊,频繁不自主瞬目。入院前4月症状加重,自觉睁眼困难,视物时需以手撑开双眼睑,且出现不自主频繁挤眼、噘嘴,不能控制,说话或精神紧张时更明显。曾用谷维素、强的松、美多巴等治疗无效。平素健康,病前无特殊疾病和用药史。查体:内科检查无异常发现, Blepharospasm, mouth and mandibular dystonia syndrome (Meige’s syndrome) is a rare disease, we now encounter two cases are reported as follows: Example 1, Zhang △△, female, 34 years old, accounting. Due to blurred vision for six months, open eyes April admission. In the first six months before admission, there was no apparent incentive for blurred vision and frequent involuntary blinking. Pre-admission symptoms increased in April, consciously eyes open difficulties, depending on the material required to open his hands double eyelids, and involuntary winking, pouting, can not control, talking or mental stress more obvious. Have used oryzanol, prednisone, mebendane and other treatment is invalid. Usually healthy, no special disease and medication history. Physical examination: no abnormal findings,