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本研究观察了低剂量阿斯匹林在行体外受精(IVF)时对卵巢反应、子宫、卵巢血流速率及着床和妊娠率的影响。 作者采用前瞻、随机、双盲安慰剂对照法,将298例因输卵管阻塞不孕患者随机分为二组,每组149例,实验组平均年龄为35.9岁,对照组为35.4岁,实验组于月经第21 d开始口服阿斯匹林100 mg/d,对照组仅口服安慰剂。所有患者于黄体中期开始给与促性腺激素释放激素激动剂(GnRHa)2 mg/d,
This study examined the effects of low-dose aspirin on ovarian response, uterine and ovarian blood flow, implantation and pregnancy rates during IVF. In a prospective, randomized, double-blind, placebo-controlled trial, 298 patients with tubal obstruction infertility were randomized into two groups of 149 patients each, with an average age of 35.9 years in the experimental group and 35.4 years in the control group Mild menstruation started aspirin 100 mg / d on day 21 and control group received placebo only. All patients were given gonadotropin-releasing hormone agonist (GnRHa) 2 mg / d in the mid luteal phase,