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研究了黄芪多糖(APS)、人参茎叶皂甙(GSL)对创伤小鼠淋巴细胞膜流动性的影响。结果显示:APS、GSL对创伤小鼠淋巴细胞膜流动性的降低具有明显的拮抗作用,并可降低创伤小鼠血清及淋巴组织中丙二醛(MDA)含量,增加谷胱甘肽(GSH)会量,提高GSH过氧化物酶(GSH-P_x)及超氧化物歧化酶(SOD)活性。表明APS、GSL可通过降低创伤后的脂质过氧化反应,进而提高淋巴细胞细胞膜的流动性。
The effects of astragalus polysaccharides (APS) and ginsenosides (GSL) on the lymphocyte membrane fluidity in wounded mice were studied. The results showed that: APS, GSL has a significant antagonistic effect on the decrease of lymphocyte membrane fluidity in traumatic mice, and can reduce malondialdehyde (MDA) content in the serum and lymphoid tissues of traumatized mice and increase the glutathione (GSH) level. Increases the activity of GSH peroxidase (GSH-P_x) and superoxide dismutase (SOD). It was shown that APS and GSL can improve the fluidity of lymphocyte membrane by reducing lipid peroxidation after trauma.