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目的 探讨视网膜色素变性 (RP)患者视网膜血流的改变情况。方法 用共焦激光扫描多普勒血流仪 (CSLDF)对 3 3例RP患者和 2 6例正常个体视乳头筛板区、颞侧盘沿和颞侧、鼻侧距盘缘约 1 50 μm处 (各两点 )的血管容量、血液流量及红细胞平均移动速率分别进行了测定。结果 RP患者组视乳头筛板区、颞侧盘沿和颞侧、鼻侧近盘周视网膜的血管容量、血液流量、红细胞平均移动速率均较正常对照组下降 ,且差异具有显著性意义 (P <0 0 5)。结论 RP患者视乳头筛板区、颞侧盘沿和近盘周视网膜血流明显降低。
Objective To investigate the changes of retinal blood flow in patients with retinitis pigmentosa (RP). Methods Confocal laser scanning Doppler flowmetry (CSLDF) was performed on the fringe area of optic disc in 33 RP patients and 26 normal individuals. Department of (two points) of vascular capacity, blood flow and erythrocyte average rate of movement were measured. Results The vascular capacity, blood flow rate and erythrocyte average velocity in optic disc area, temporal pannus and temporal side of nasopharyngeal and retina in RP group were significantly lower than those in normal control group (P <0 0 5). Conclusion RP patients with optic disc area, temporal pannus and proximal retinal blood flow decreased significantly.