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目的探讨阿托伐他汀在老年脑梗死患者治疗中的作用。方法选择我院2010年8月～2011年12月就诊的老年脑梗死患者43例,分为观察组(n=22)和对照组(n=21),对照组给予复方丹参静脉滴注,观察组在此基础上加用阿托伐他汀口服治疗,疗程为2周,观察比较两组疗效及神经缺损评分。结果观察组治愈5例,显效8例,有效6例,恶化2例,死亡1例,总有效率为86.36%,对照组治愈3例,显效6例,有效5例,恶化4例,死亡3例,治疗有效率为66.67%,两组有效率比较,差异有统计学意义(P<0.05)。治疗后观察组神经功能缺损评分优于对照组,两组治疗后比较差异有统计学意义(P<005)。结论在常规治疗基础上应用阿托伐他汀对老年脑梗死疗效较好,值得临床推广应用。
Objective To investigate the role of atorvastatin in the treatment of elderly patients with cerebral infarction. Methods Forty-three elderly patients with cerebral infarction from August 2010 to December 2011 were selected and divided into observation group (n = 22) and control group (n = 21). The control group received intravenous infusion of compound Salvia miltiorrhiza. Group based on this plus oral treatment with atorvastatin, course of treatment for 2 weeks, observed and compared the two groups efficacy and neurological deficit score. Results The observation group was cured in 5 cases, markedly effective in 8 cases, effective in 6 cases, exacerbation in 2 cases and death in 1 case, the total effective rate was 86.36%. The control group cured 3 cases, markedly effective in 6 cases, effective in 5 cases, exacerbated in 4 cases, died 3 Cases, the effective rate was 66.67%, the two groups were compared, the difference was statistically significant (P <0.05). After treatment, the score of neurological deficit in observation group was better than that in control group. There was significant difference between the two groups after treatment (P <0.05). Conclusion The application of atorvastatin on elderly patients with cerebral infarction has better curative effect than conventional treatment, which is worthy of clinical application.