Multifunctional TiO2/Ag composite nanowires are fabricated with a hydrothermal method by precipitating Ag nanoparticles(NPs) on the surfaces of TiO2nanowires.This hierarchical one-dimensional(1D) nanostructure can be used as a surface enhanced Raman scattering(SERS) substrate with high sensitivity,for detecting the rhodamine 6G(R6G)in a wide range of low concentrations(from 1×10-6M to 1×10-12M).In addition,the substrate can be self-cleaned under the irradiation of ultraviolet(UV) light due to the superior photocatalytic capacity of the TiO2/Ag composite nanostructure,making the recycled use of SERS substrates closer to reality.With both the evident SERS performance and high efficiency of photocatalytic capacity,such TiO2/Ag composite nanowires demonstrate considerable potential in the chemical sensing of organic pollutants. Multifunctional TiO2 / Ag composite nanowires are fabricated with a hydrothermal method by precipitating Ag nanoparticles (NPs) on the surfaces of TiO2 nanowires. This hierarchical one-dimensional (1D) nanostructure can be used as a surface enhanced Raman scattering (SERS) substrate with high sensitivity , for detecting the rhodamine 6G (R6G) in a wide range of low concentrations (from 1 × 10-6 M to 1 × 10-12 M) .In addition, the substrate can be self-cleaned under the irradiation of ultraviolet (UV) light due to the superior photocatalytic capacity of the TiO2 / Ag composite nanostructure, making the recycled use of SERS substrates closer to reality. Both of the evident SERS performance and high efficiency of photocatalytic capacity, such TiO2 / Ag composite nanowires demonstrate considerable potential in the chemical sensing of organic pollutants.