肿瘤的浸润和转移是一个复杂的多步骤多环节的过程 ,在整个转移过程中肿瘤细胞脱离原发灶 ,黏附于细胞外基质 (extracellularmatrix ,ECM ) ,经降解基质进行移动并侵及淋巴管和血管 ,从而发生转移。细胞与细胞 ,细胞与ECM之间的黏附和相互作用 ,由一系列被称为细胞黏附分子的物 Tumor invasion and metastasis is a complex multi-step and multi-step process. During the whole metastasis, the tumor cells detach from the primary tumor, adhere to the extracellular matrix (ECM), move through the degradation matrix and invade lymphatic vessels and Blood vessels, and thus the transfer occurs. The adhesion and interaction between cells and cells, cells and ECMs are mediated by a series of substances known as cell adhesion molecules