论文部分内容阅读
关于中枢去甲肾上腺素(NE)在心血管活动调节中的作用,以往的研究多侧重于脑内。本文从脊髓水平进行了探讨。实验用颈总动脉和脊髓蛛网膜下腔植入导管的麻醉动物完成。结果如下: 一、脊髓蛛网膜下腔注射(ith)NE的降压效应:大鼠ith 2.5～10μgNE,引起与剂量相关的降血压(-9±2～-20±4％)与减慢心率(-5±4～-17±4％)作用。预先ithα阻断剂酚妥拉明、α_1阻断剂哌唑嗪或α_2阻
Regarding the role of central norepinephrine (NE) in the regulation of cardiovascular activity, previous studies have mostly focused on the brain. This article discusses the level of spinal cord. Experiments with the common carotid artery and spinal subarachnoid catheterization anesthesia animals completed. The results were as follows: 1. The antihypertensive effect of neuraxial injection of ith NE into the spinal cord: ith 2.5 ~ 10μgNE in the rat caused a dose-dependent hypotensive (-9 ± 2 ~ -20 ± 4%) and slowed heart rate (-5 ± 4 ~ -17 ± 4%) effect. Pre-ithα blocker phentolamine, α_1 blocker prazosin or α_2 block