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探讨如何选择女性急性单纯膀胱炎多剂量疗法的最佳方案 ,如何鉴别无全身症状的肾盂肾炎。方法 :符合入选条件的女性急性单纯膀胱炎患者共 92例 ,随机分配为 3日疗法组、5日疗法组和 7日疗法组 ,予复方新诺明和小苏打每次 2片 ,每日 2次口服。疗程结束后连续 3天、1周及 4周复查尿常规、作正规清洁中段尿细菌培养 ,若为真性细菌尿 ,则做药物敏感试验 ,同时行尿β2 -微球蛋白 ( β2 —MG)检查。结果 :停止治疗后 4周 3日疗法组、5日疗法组和 7日疗法组的治愈率分别为 76.7%、83 .9%、87.1%;复发依次为 4、1、1例 ;重新感染则依次为 1、1、2例。结论 :对于女性单纯膀胱炎多剂量治疗方案 ,我们推荐 5日疗法和尿 β2 MG结合作为尿感中区分膀胱炎和肾盂肾炎的最佳方法
Discuss how to choose the best solution of multiple dose therapy for acute cystitis in women and how to identify pyelonephritis without systemic symptom. Methods: A total of 92 female patients with acute cystitis were enrolled in this study. They were randomized into 3-day treatment group, 5-day treatment group and 7-day treatment group. The patients were given 2 tablets of sulfamethoxazole and sodium bicarbonate twice daily, oral. After the end of the course of treatment, the urine routine was reviewed for 3 consecutive days, 1 week and 4 weeks, and urine culture was conducted in the middle stage of regular cleanup. If the test was true bacterial urine, drug sensitivity test was performed and urine β2-microglobulin (β2-MG) . Results: After 4 weeks of treatment, the cure rates on the 3rd, 4th and 7th treatment groups were 76.7%, 83.9% and 87.1%, respectively; the recurrences were 4, Followed by 1,1,2 cases. Conclusions: For women with multiple cystitis alone, we recommend a combination of 5-day therapy and urinary β2-MG as the best method to distinguish cystitis from pyelonephritis