杀灭菊酯(Fenvalerate,S-5602)是人工合成的除虫菊酯杀虫剂,对棉花、果树、蔬莱等多种作物有良好药效。浙江省粮科所拟将杀灭菊酯与杀螟松、马拉硫磷、甲基嘧啶硫磷等联合使用,以保藏粮食。由于杀灭菊酯在我国是初次生产尚未经毒理鉴定的新农药,故需进行系列毒理试验。我组在动物毒理试验中,发现微核试验(10mg/kg)阳性,因此,选用致突项目中比骨髓染色体畸变指标更 Fenvalerate (S-5602) is a synthetic pyrethroid insecticide with good efficacy on a wide range of crops including cotton, fruit trees and vegetables. Zhejiang Food Bureau intends to kill fenvalerate and fenitrothion, malathion, methyl pyripyrosine and other joint use to preserve food. As fenvalerate in China is the first production of new pesticides have not been identified toxicological, it is necessary to conduct a series of toxicological tests. My group in animal toxicology test found that the micronucleus test (10mg / kg) positive, therefore, the selection of the project than the bone marrow chromosome aberration more indicators