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目的分析川崎病(KD)患儿的临床表现,探讨前降钙素(PCT)在不完全KD早期辅助诊断中的意义。方法回顾性分析2007年1月-2008年12月浙江大学医学院附属儿童医院收治的83例KD患儿(KD组,包括63例典型KD和20例不完全KD)和83例因细菌感染性疾病住院的患儿(感染组)外周血WBC、CRP、ESR、PCT等结果 ,应用SPSS12.0软件比较2组各指标间的差异。结果 KD组与感染组比较,WBC、CRP、ESR等差异均无统计学意义(Pa>0.05),但PCT差异有统计学意义(P<0.001);PCT在典型KD与不完全KD组间分布的差异无统计学意义(χ2=0.298,P=0.585)。结论 PCT可作为不完全KD早期辅助诊断的实验室依据之一。
Objective To analyze the clinical manifestations of children with Kawasaki disease (KD) and explore the significance of procalcitonin (PCT) in the early diagnosis of incomplete KD. Methods A retrospective analysis of 83 children with KD (KD group, 63 cases of typical KD and 20 cases of incomplete KD) and 83 cases of children with KD admitted to Children’s Hospital of Zhejiang University School of Medicine from January 2007 to December 2008 were retrospectively analyzed. WBC, CRP, ESR, PCT and other results of children hospitalized with disease (infection group), SPSS12.0 software was used to compare the differences between the two groups of indicators. Results There were no significant differences in WBC, CRP and ESR between the KD group and the infected group (P> 0.05), but the differences were statistically significant (P <0.001). The distribution of PCT between the typical KD group and the incomplete KD group The difference was not statistically significant (χ2 = 0.298, P = 0.585). Conclusion PCT can be used as one of the laboratory bases for the early diagnosis of incomplete KD.