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对2020年6月至2021年8月浙江省江山市人民医院诊治的120例无积水肾下盏小结石患者，分为药物组、振动组和联合组，每组各40例，分别采用口服枸橼酸氢钾钠、物理振动排石术（EPVL）、EPVL联合枸橼酸氢钾钠治疗，枸橼酸氢钾钠剂量为10.0 mg/d（早、中为2.5 mg，晚为5.0 mg），EPVL持续振动排石共18 min，振动频率2 800次/min、振幅5 mm。视结石排出情况分别于第1次治疗后1、2、4周后复查泌尿系CT、外周血常规、尿常规、肾功能等，并监测早晚体温和尿色变化，观察各组治疗1、2、4周的结石排出率及并发症发生情况n 。治疗后，3组结石总排出率为39.2%（47/120）。各组每周的排出率比较，振动组、联合组排出率均高于药物组（n P0.05），无严重并发症，治疗后均恢复正常。提示，EPVL可促进无积水肾下盏小结石的排出，EPVL联合枸橼酸氢钾钠可提高结石的排出率。n “,”A prospective randomized controlled study was conducted in 120 patients with hydronephrosis-free lower calyceal calculi in Jiangshan People′s Hospital from June 2020 to August 2021. Patients were divided into drug group, vibration group and combination group by random number table method with 40 cases in each group. The drug group was treated with potassium hydrogen citrate sodium, the vibration group was treated with external physical vibration lithotripsy (EPVL), and the combination group was treated with EPVL combined with potassium hydrogen citrate sodium. The renal stone discharge rate and complications were observed and compared among three groups 1, 2 and 4 weeks after treatment. The overall discharge rate in 120 patients was 39.2%(47/120). The discharge rate of vibration group and combination group were higher than that of drug group (n P<0.05). There were no significant differences in stone discharge rate at 1 and 2 weeks after treatment between vibration and combination group (n P=0.63 and 0.14), while the calculi discharge rate at 4 weeks after treatment in combination group was higher than that in vibration group (n P=0.03).The overall incidence of complications in 120 patients was 12.5% (15/120), that of drug group, vibration group and combination group was 7.5%(3/40), 15.0%(6/40), and 15.0% (6/40), respectively (n P<0.05). No serious complication occurred, and all patients recovered well after treatment. The results suggest that EPVL can promote the discharge of small calyceal calculi in hydronephrosis-free patients, and potassium hydrogen citrate sodium can further facilities the discharge of renal stone.n