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目的 探讨糖尿病合并冠心病的影响因素及其防治。方法 比较年龄相仿、初诊糖尿病合并冠心病与冠心病病人血糖、血脂、血清胰岛素、胰岛素抵抗指数、胰岛素敏感指数各参数的差异 ,并分析胰岛素抵抗与血脂各参数的相关性。结果 糖尿病合并冠心病组空腹血糖 (11.16± 2 .77mmol/L)、血清甘油三酯 (2 .76± 2 .12mmol/L)、胰岛素抵抗指数 (8.93±7.13)显著高于冠心病组 ,血清胰岛素 (2 2 .0 2± 2 0 .47μu/ml)、血清总胆固醇酯 (4.84± 1.4mmol/L)、LDL -C(2 .43± 0 .87mmol/L) ,HDL -C(1.2 2± 0 .48mmol/L)与冠心病组无显著性差异。结论 高血糖、高甘油三酯血症和胰岛素抵抗是影响糖尿病合并冠心病的重要因素 ,积极治疗高血糖、高甘油三酯血症和胰岛素抵抗对予防糖尿病合并冠心病具有重要意义。
Objective To investigate the influencing factors and prevention and cure of diabetes complicated with coronary heart disease. Methods The differences of blood glucose, blood lipids, serum insulin, insulin resistance index and insulin sensitivity index in patients with newly diagnosed diabetes mellitus complicated with coronary heart disease and coronary heart disease were compared. The correlation between insulin resistance and blood lipid parameters was analyzed. Results The fasting blood glucose (11.16 ± 2. 77mmol / L), serum triglyceride (2.76 ± 2.12mmol / L) and insulin resistance index (8.93 ± 7.13) in patients with diabetes mellitus and coronary heart disease were significantly higher than those in patients with coronary heart disease (2.24 ± 1.4mmol / L), LDL-C (2.43 ± 0.87mmol / L), HDL-C (1.2 2 ± 0.48mmol / L) and coronary heart disease group no significant difference. Conclusions Hyperglycemia, hypertriglyceridemia and insulin resistance are the important factors affecting the diabetes mellitus with coronary heart disease. Active treatment of hyperglycemia, hypertriglyceridemia and insulin resistance are important for the prevention of diabetes complicated with coronary heart disease.