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目的 探讨不同脑栓塞病人的血液流变学、体外模拟血栓形成和 D-二聚体含量的关系。方法 用N6A血流变仪和标准摆动式旋转 CAST法对 43例脑栓塞患者和 5 1例健康人进行血液流变学及体外模拟血栓的试验 ,并用胶乳定性法及定量法测定 D-二聚体含量。结果 患者血液流变学显著高于健康人、模拟血栓湿重和指数 Q值与健康人有显著差异 ( P<0 .0 5 ) ,血栓长度改变不明显 ( P>0 .0 5 ) ;血浆 D-二聚体含量水平与年龄有关 ,年龄小于 40 y组与大于 40 y组的差异有非常显著性 ( P<0 .0 1 )。结论 对脑栓塞病人进行血液流变学及体外模拟血栓检查和血浆 D-二聚体检测对了解血栓形成具有重要意义
Objective To investigate the relationship between hemorrheology, simulated thrombosis and D-dimer in patients with different cerebral embolism. Methods The hemorheology and in vitro simulated thrombosis of 43 patients with cerebral embolism and 51 healthy controls were tested by N6A hematological rheometer and standard swing rotary CAST method. The latex qualitative and quantitative methods were used to determine the D-dimer Body content. Results The hemorheology of patients was significantly higher than that of healthy people (P <0.05), and the change of thrombus length was not significant (P> 0.05) The level of D-dimer was related to age. There was a significant difference between the age less than 40 y and the more than 40 y (P <0.01). Conclusions Hemorheology, in vitro simulated thrombosis and plasma D-dimer testing in patients with cerebral embolism are important for understanding thrombosis