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目的对比丙泊酚与七氟烷在患儿全身麻醉中对其血流动力学、术后苏醒质量的影响。方法本研究纳入2015年5月~2016年5月择期全麻手术患儿100例,随机分成2组,每组50例,A组采用丙泊酚静脉注射麻醉,B组采用七氟烷吸入麻醉,观察两组患儿血流动力学情况、术后苏醒质量。结果 A组患儿手术开始5min后的收缩压(SBP)、舒张压(DBP)、心率(HR)均明显低于麻醉诱导前(P<0.05),七氟烷组患儿同期的SBP、DBP、HR和麻醉诱导前比较,差异无统计学意义(P>0.05)。此外,A组、B组在术后苏醒时间和定向力时间的比较均无统计学差异(P>0.05),但B组患儿手术出现恶心呕吐、躁动较A组多。结论与丙泊酚相比,七氟烷吸入麻醉应用于小儿全身麻醉有更稳定的血流动力学优势,在术后苏醒质量上,七氟烷在抑制术后躁动和恶心呕吐方面比丙泊酚差。
Objective To compare the effects of propofol and sevoflurane on hemodynamics and postoperative wakefulness during general anesthesia in children. Methods 100 children with elective general anesthesia were enrolled in this study from May 2015 to May 2016. They were randomly divided into 2 groups (50 in each group): group A received propofol intravenous anesthesia; group B received sevoflurane inhalation anesthesia The hemodynamics and postoperative recovery quality were observed in both groups. Results SBP, DBP and HR in group A were significantly lower than those before induction of anesthesia (P <0.05) 5 min after the start of operation, SBP, DBP , HR and anesthesia before induction, the difference was not statistically significant (P> 0.05). In addition, there was no significant difference between the time of recovery and the time of orientation in group A and group B (P> 0.05). However, there was more nausea and vomiting in group B than in group A. Conclusion Compared with propofol, inhalation of sevoflurane anesthesia in pediatric general anesthesia has a more stable hemodynamic advantages, postoperative recovery quality, sevoflurane in the inhibition of postoperative agitation and nausea and vomiting than the propofol Poor phenol.