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[目的]了解35岁以上人群腰围与糖耐量情况,探讨影响糖耐量正常人群糖耐量转归的因素,为糖尿病预防提供科学依据。[方法]在青岛市城乡选取2006年糖耐量正常的684名35～74岁人群,测量其腰围值,3年后进行随访。[结果]2006年684名糖耐量正常者中,腹型肥胖罹患率为53.22%。3年后随访上述684人,IGR累积发病率为28.07%,其中腹型肥胖组为34.89%,腰围正常组为20.31%(P<0.01);DM累积发病率为3.51%,其中腹型肥胖者为4.67%,腰围正常组为2.19%(P>0.05)。684人中,2006年腰围为82.38±9.23cm,2009年腰围为85.29±9.45cm(P<0.01)。多因素非条件Logistic回归分析结果,影响糖耐量情况的因素有收缩压(SBP)、腰围(WC)、低密度脂蛋白胆固醇(LDL)、总胆固醇(TC)、尿酸(UA),OR值分别为1.011、1.047、0.643、1.584、1.003。[结论]腹型肥胖者较腰围正常者易发生IGR;收缩压高、腰围值高、低密度脂蛋白胆固醇含量低、总胆固醇含量高、尿酸高的人容易转归为IGR和/或DM。
[Objective] To understand the situation of waist circumference and glucose tolerance in people over 35 years of age and to explore the factors affecting the glucose tolerance of normal population with impaired glucose tolerance and to provide a scientific basis for the prevention of diabetes. [Method] A total of 684 35-74-year-old population with normal glucose tolerance in 2006 were selected in urban and rural areas of Qingdao. Their waist circumference were measured and followed up for 3 years. [Results] In 684 normal subjects with impaired glucose tolerance, the prevalence of abdominal obesity in 2006 was 53.22%. After 3 years follow-up, the cumulative incidence of IGR was 28.07%, including 34.89% in abdominal obesity group and 20.31% in normal waist circumference group (P <0.01). The cumulative incidence of DM was 3.51% Was 4.67%, and the normal waist circumference was 2.19% (P> 0.05). Among 684 people, the waist circumference was 82.38 ± 9.23 cm in 2006 and 85.29 ± 9.45 cm in 2009 (P <0.01). The multivariate non-conditional logistic regression analysis showed that SBP, WC, LDL, TC, UA and OR were the main influencing factors of glucose tolerance For 1.011, 1.047, 0.643, 1.584, 1.003. [Conclusion] The abdominal obesity is more likely to develop IGR than the normal waist. The patients with high systolic pressure, high waist circumference, low LDL cholesterol, high total cholesterol and high uric acid are easily classified as IGR and / or DM.