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目的探讨新生儿胆红素脑病的发病因素,为其防治提供依据。方法分析36例新生儿胆红素脑病的病因,比较警告期与痉挛期之间,不同发病日龄组之间血清胆红素值。结果①病因以溶血性因素占首位(占72.09%),其次是感染因素(占27.91%);②围生因素是影响胆红素脑病发生的重要因素;③警告期与痉挛期组间血清胆红素差异无显著性;④不同发病日龄组间血清胆红素差异无显著性。结论加强围生期保健,减少早产、感染、避免院外生产是减少新生儿胆红素脑病的关键。
Objective To explore the etiological factor of neonatal bilirubin encephalopathy and provide evidence for its prevention and treatment. Methods The etiology of 36 cases of neonatal bilirubin encephalopathy was analyzed. The serum bilirubin value was compared between the warning period and the spasticity period, and between different age groups. Results ① The cause of hemolytic disease accounted for the top (72.09%), followed by infection (27.91%); ②Peritoneal factors are important factors that affect the occurrence of bilirubin encephalopathy; ③While between the warning period and spasticity serum gallbladder There was no significant difference in the level of bilirubin between the two groups. Conclusion Strengthening perinatal care, reducing preterm delivery, infection and avoiding out-of-hospital production are the keys to reduce neonatal bilirubin encephalopathy.