论文部分内容阅读
目的 :探讨辽宁大连地区中老年人群中颈围与高血压间的相关性。方法 :对参加“2型糖尿病肿瘤发病风险流行病学研究”基线调查的辽宁省大连市社区居民进行随访,共纳入符合标准的研究对象2 623名,对其进行问卷信息收集,并进行体格检查及生化检测。根据颈围四分位数水平,将其分为Q1、Q2、Q3及Q4组,比较各组间的收缩压、舒张压和高血压患病率及其他临床指标。结果:颈围四分位Q1、Q2、Q3及Q4组间的收缩压、舒张压差异均有统计学意义,收缩压分别为(121.4±16.9)、(122.6±16.7)、(128.5±18.6)、(132.0±18.2)mm Hg,舒张压分别为(70.8±9.7)、(73.1±9.4)、(75.7±10.5)及(77.4±10.0)mm Hg(P均<0.001),且随着颈围的增加,收缩压及舒张压逐渐升高。4组的高血压患病率分别为16.8%、17.7%、29.3%及38.5%,差异有统计学意义(χ2=104.955,P<0.001)。颈围与收缩压及舒张压均呈正相关(r为0.273、0.324,P<0.05)。多元线性逐步回归分析显示,颈围水平增加与收缩压、舒张压水平增加间显著相关。Logistic回归分析结果显示,颈围每增加一个标准差,高血压患病风险增加41.2%(OR=1.412,95%CI为1.216~1.639,P<0.001)。结论 :大连地区中老年人群中,随着颈围增加,收缩压及舒张压水平逐渐增加,高血压患病率亦有逐渐增加趋势,研究结果提示颈围是大连地区中老年人高血压患病的独立危险因素。
Objective: To investigate the correlation between neck circumference and hypertension in middle-aged and elderly population in Dalian, Liaoning Province. Methods: The community residents in Dalian City, Liaoning Province, who participated in the “Epidemiological Study of Risk of Type 2 Diabetes Mellitus” were followed up and included 2 623 eligible patients. The questionnaires were collected and conducted Physical examination and biochemical tests. According to the quartile level of neck circumference, it was divided into Q1, Q2, Q3 and Q4 groups, and the systolic blood pressure, diastolic blood pressure and the prevalence of hypertension and other clinical indicators were compared. Results: There were significant differences in systolic and diastolic blood pressure between Q1, Q2, Q3 and Q4 in the cervical quartile. The systolic blood pressure were (121.4 ± 16.9), (122.6 ± 16.7) and (128.5 ± 18.6) , (132.0 ± 18.2) mm Hg and diastolic blood pressure (70.8 ± 9.7), (73.1 ± 9.4), (75.7 ± 10.5) and (77.4 ± 10.0) mm Hg, respectively Increase, systolic blood pressure and diastolic blood pressure gradually increased. The prevalence rates of hypertension in the four groups were 16.8%, 17.7%, 29.3% and 38.5%, respectively, with statistical significance (χ2 = 104.955, P <0.001). Neck circumference and systolic and diastolic blood pressure were positively correlated (r = 0.273,0.324, P <0.05). Multivariate linear stepwise regression analysis showed that the increase of neck circumference was significantly correlated with systolic and diastolic blood pressure levels. Logistic regression analysis showed that the risk of hypertension was increased by 41.2% (OR = 1.412, 95% CI 1.216-1.639, P <0.001) for each additional standard deviation of neck circumference. Conclusion: In middle-aged and elderly population in Dalian, as the neck circumference increases, the systolic and diastolic blood pressure levels increase gradually, and the prevalence of hypertension also increases gradually. The results suggest that the neck circumference is the prevalence of hypertension in middle-aged and elderly people in Dalian Of independent risk factors.