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作者用ELISA法研究了37例慢性前列腺炎(CP)患者(其中合并不育者23例,有生育力者14例)的血清及精浆抗精子抗体(AsAb)阳性率及其与精液常规质量的联系,发现CP者与正常人间的血清AsAb阳性率无明显差别(P>0.05),说明血清AsAb与CP及其不育无明显关系。CP者的精浆AsAb阳性率(56.76％)离于正常人(18.18％)(P<0.05),且CP不育者(69.56％)又高于CP生育者(35.71％)(P<0.05),说明CP可引起精浆AsAb升高,进而降低生育力。进一步分析发现精浆AsAb阳性者的精子活动力明显降低(P<0.01),提示精浆AsAb可通过降低精子活动力进而引起不育。
The authors studied the positive rate of serum and sperm anti-sperm antibody (AsAb) in 37 chronic prostatitis (CP) patients (including 23 cases of infertility and 14 cases of fertility) using ELISA. Found no significant difference in serum AsAb positive rate between CP and normal (P> 0.05), indicating that serum AsAb and CP and their infertility no significant relationship. The positive rate of AsAb in the seminal plasma of CP patients (18.7%) was significantly lower than that in normal subjects (P <0.05), and CP infertility patients (69.56% vs 35.71%, P <0.05) , Indicating that CP can cause seminal plasma AsAb increased, thereby reducing fertility. Further analysis found that sperm motility in AsAb-positive seminal plasma was significantly lower (P <0.01), suggesting that seminal plasma AsAb may cause infertility by reducing sperm motility.