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目的观察5-氨基酮戊酸-光动力(5-aminolevulinic acid photodamic therapy,ALA-PDT)疗法治疗尖锐湿疣的疗效,探讨最佳护理方案。方法将入选患者随机分为常规护理组(149例)和综合护理组(150例),两组均予5-氨基酮戊酸-光动力疗法治疗,在此基础上,常规护理组仅进行常规护理,综合护理组进行全面、细致和人性化的综合护理措施。两组均随访半年,并判定疗效。结果综合护理组中143例(95.33%)完全缓解,5例(3.33%)部分缓解,2例(1.33%)无反应,随访半年,14例(9.79%)复发;常规护理组依次为135例(90.60%)、8例(5.37%)、6例(4.03%)和25例(18.52%)。两组的完全缓解率相比,差异无统计学意义(P>0.05),但综合护理组的复发率显著低于常规护理组,差异有统计学意义(P<0.05)。结论采用ALA-PDT疗法治疗尖锐湿疣时宜采用全面、细致和人性化的综合护理措施。
Objective To observe the curative effect of 5-aminolevulinic acid photodamic therapy (ALA-PDT) on condyloma acuminatum and to explore the best nursing plan. Methods The patients were randomly divided into routine care group (n = 149) and comprehensive care group (n = 150). Both groups were treated with 5-aminolevulinic acid-photodynamic therapy. On the basis of this, Nursing, comprehensive care group to conduct a comprehensive, detailed and humane comprehensive care measures. Two groups were followed up for six months, and determine the efficacy. Results In the comprehensive care group, 143 cases (95.33%) were completely relieved, 5 cases (3.33%) partially relieved, 2 cases (1.33%) did not respond, followed up for half a year and 14 cases (9.79%) relapsed; (90.60%), 8 cases (5.37%), 6 cases (4.03%) and 25 cases (18.52%). There was no significant difference in the complete remission rate between the two groups (P> 0.05), but the relapse rate of the comprehensive care group was significantly lower than that of the conventional nursing group (P <0.05). Conclusion ALA-PDT treatment of genital warts should adopt a comprehensive, detailed and humane comprehensive care measures.