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目的:探讨射频消融治疗晚期肺癌的临床疗效及安全性。方法:对12例原发性晚期肺癌和肺转移癌病人,在局麻下进行射频消融治疗,8例在CT下定位,2例在胸腔镜直视下进行。消融温度56～90°,治疗时间为30～120分钟。结果:12例病人共进行14次射频消融,其中2例进行2次。术中6例伴有不同程度的疼痛,3例出现不同程度的咳嗽、咳血。治疗后4例出现不同程度的肺水肿,发生气胸2例,血胸1例,住院治疗期间全组无死亡病例。结论:经皮射频消融术治疗晚期肺癌,损伤小,安全,病人易于接受,治疗有效,远期效果需进一步观察。
Objective: To investigate the clinical efficacy and safety of radiofrequency ablation in the treatment of advanced lung cancer. Methods: Twelve patients with primary advanced lung cancer and metastatic lung cancer underwent radiofrequency catheter ablation under local anesthesia. Eight patients underwent CT localization and two underwent thoracoscopic surgery. Ablation temperature 56 ~ 90 °, the treatment time is 30 to 120 minutes. Results: A total of 12 radiofrequency ablation procedures were performed in 12 patients, 2 of which were performed 2 times. Intraoperative 6 patients with varying degrees of pain, 3 cases of varying degrees of cough, hemoptysis. There were 4 cases of pulmonary edema with different degrees after treatment, 2 cases of pneumothorax and 1 case of hemothorax. No deaths occurred in the whole group during hospitalization. Conclusion: Percutaneous radiofrequency ablation for the treatment of advanced lung cancer has less injury and safety, is easy to be accepted by patients and effective in treatment. The long-term effect needs further observation.