目的：观察马蔺子素在恶性肿瘤中的放射增敏和毒付作用。方法：52例病人进行了放疗加口服马蔺子素的观察。观察组口服lq7611120mg／次，2次／日，分别在放疗前后各2小时服用；对照组不服药仅单纯放疗。结果：按UICC实体瘤观察指标和WHO推荐的毒付反应分级标准，观察组的原发灶和转移灶近期缓解率好于对照组，毒付作用未增加。结论：该药有一定的增敏作用，毒付作用可以耐受，建议进一步扩大临床试用。 Objective: To observe the radiosensitization and toxic effects of melittin in malignant tumors. Methods: 52 patients were treated with radiotherapy plus oral quercetin. The observation group was orally given lq7611120mg/time, 2 times/day, respectively, taken 2 hours before and after radiotherapy; the control group was not treated with radiotherapy alone. RESULTS: According to the UICC solid tumor observation index and the titration criteria recommended by the WHO, the immediate remission rate of the primary tumor and metastasis in the observation group was better than that of the control group, and the toxic effect did not increase. Conclusion: The drug has a certain sensitizing effect, and the toxin effect can be tolerated. It is suggested that clinical trials be further expanded.