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5. Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats

Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats

来源 :国际肝胆胰疾病杂志：英文版 | 被引量 : 0次 | 上传用户：ganjinwei2001

【摘 要】

：

BACKGROUND: Prostacyclin has been shown to increase portal hypertension, but the mechanism is unclear. This study aimed to investigate whether the overproductio

【作 者】

：

De-Jun Liu Wei Chen Yan-Miao H 

【机 构】

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DepartmentofBiliary-PancreaticSurgery

【出 处】

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国际肝胆胰疾病杂志：英文版

【发表日期】

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2014年4期

【关键词】

：

血管收缩 前列环素 肝硬化 大鼠 内脏 WESTERN印迹法 去甲肾上腺素 蛋白激酶A portal hypertension prostacyclin ind 

【基金项目】

：

supported by a grant from the Shanghai Science and Technology Commission（10411965200）

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BACKGROUND: Prostacyclin has been shown to increase portal hypertension, but the mechanism is unclear. This study aimed to investigate whether the overproduction of prostacyclin(PGI2) in cirrhosis participates in the splanchnic vascular hyporesponsiveness

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