目的:探索有效的护理干预模式,最大限度降低初产妇产后抑郁症发生率,促进初产妇产后抑郁快速康复,更好地促进婴儿生长发育,改善家庭成员之间、夫妻之间的关系。方法:自行设计《产妇抑郁的影响因素调查问卷》和采用Edinburgh产后抑郁量表在产后2周及产妇出院后42 d内对初产妇抑郁发生率进行调查,探讨产后抑郁发生的主要危险因素,并通过有效干预措施,观察是否可以降低产后抑郁症发生率。结果:调查结果显示总体抑郁发生率由产后2周的21.5%降至产后42 d的5.9%,差异具有统计学意义(P<0.05);轻度抑郁发生率由产后2周的19%降至产后42 d的5.6%;中重度抑郁发生率由产后2周的1.25%降至产后42 d的0.3%,差异具有统计学意义(P<0.05)。结论:通过有效的护理干预可以显著降低初产妇产后抑郁的发生率。 Objective: To explore an effective nursing intervention model to minimize the incidence of postpartum depression in primipara, to promote rapid recovery of primipara postpartum depression, to better promote infant growth and development, to improve the relationship between family members, husband and wife. Methods: To investigate the incidence of depression in primipara after 2 weeks of postpartum and within 42 days after discharge from the postnatal depression questionnaire by questionnaire of influencing factors of maternal depression, and explore the main risk factors of postpartum depression Through effective interventions, observe whether it can reduce the incidence of postpartum depression. Results: The survey showed that the overall incidence of depression decreased from 21.5% at 2 weeks postpartum to 5.9% at 42 days postpartum, with a significant difference (P <0.05). The incidence of mild depression decreased from 19% at 2 weeks postpartum The incidence of moderate and severe depression was reduced from 1.25% at 2 weeks postpartum to 0.3% at 42 days postpartum. The difference was statistically significant (P <0.05). Conclusion: The incidence of postpartum depression in primipara can be significantly reduced by effective nursing intervention.