目的研究急性脑梗死患者脑磁图(magnetoencephalography,MEG)体感诱发磁场(somatosensoryevokedmagneticfields,SEFs)和听觉诱发磁场(auditoryevokedmagneticfields,AEFs)时间参数变化。方法使用306通道MEG机对15例急性脑梗死患者进行SEFs和AEFs检测;同时检测健康志愿者25例作为对照。结果SEFs的最基本波形为M20,患者组M20潜伏期患侧为(23.3±1.5)ms,健侧为(21.9±1.3)ms,正常对照组为(20.6±1.1)ms,患者组明显延迟(P<0.01)。AEFsM100患者组潜伏期为(97.0±6.0)ms,正常对照组为(89.3±27.9)ms;患者组明显延迟(P<0.05)。结论MEG可灵敏、客观地检测出急性脑梗死患者体感和听觉皮层中枢功能损伤。 Objective To study the time parameters of somatosensory evoked magnetic fields (SEFs) and auditory evoked magnetic fields (AEFs) in patients with acute cerebral infarction. Methods SEFs and AEFs were measured in 306 patients with acute cerebral infarction using a 306-channel MEG machine. Twenty-five healthy volunteers were also used as controls. Results The most basic waveform of SEFs was M20. The incidence of M20 latency was (23.3 ± 1.5) ms, (21.9 ± 1.3) ms in healthy group and (20.6 ± 1.1) ms in normal control group, and was significantly delayed in patients with P <0.01). The incubation period of AEFsM100 patients was (97.0 ± 6.0) ms and that of the normal controls was (89.3 ± 27.9) ms. The patient group was significantly delayed (P <0.05). Conclusion MEG can sensitively and objectively detect central and functional impairment of somatosensory and auditory cortex in patients with acute cerebral infarction.