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目的分析阻塞性黄疸患者的十二指肠病变。方法总结确诊为阻塞性黄疸的患者150例十二指肠球炎及溃疡发生情况,并以128例无阻塞性黄疸的肝、胆、胰疾病的患者作为对照。结果 150例阻塞性黄疸患者中:低位阻塞119例,高位阻塞31例,其十二指肠炎症与溃疡的检出率分别为20%(24/119),8.4%(10/119)和9.6%(3/31),9.6%(3/31),对照组为7.0%(9/128)和4.7%(6/128)。结论低位阻塞性黄疸患者十二指肠炎症和溃疡的检出率明显高于对照组和高位阻塞组(P<0.01),而高位阻塞性黄疸组与对照组间检出率无明显差别(P>0.05)。对低位组黄疸患者应给适当的制酸剂,以治疗和预防并发的十二指肠溃疡。
Objective To analyze duodenal lesions in patients with obstructive jaundice. Methods 150 patients with obstructive jaundice were enrolled in this study. Fifty-two patients with duodenal inflammation and ulcer were enrolled in this study. 128 patients with non-obstructive jaundice were enrolled as controls. Results Among the 150 patients with obstructive jaundice, 119 cases had low obstruction and 31 cases had high obstruction. The detection rates of duodenal inflammation and ulcer were 20% (24/119), 8.4% (10/119) and 9.6% % (3/31), 9.6% (3/31) in the control group and 7.0% (9/128) and 4.7% (6/128) in the control group. Conclusions The detection rate of duodenal inflammation and ulcer in patients with low obstructive jaundice is significantly higher than that in control group and high obstruction group (P <0.01), while there is no significant difference between high obstructive jaundice group and control group (P > 0.05). Low-grade patients with jaundice should be given appropriate antacids to treat and prevent concurrent duodenal ulcer.