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本文报道用氩气替代氦气所配之肺CO弥散量测试气体,对120例健康成人(15～80岁)进行标准化一次呼吸法肺CO弥散量(D_LCO_(SB))测定,取得了不同性别、不同年龄组测值的均值、标准差及男、女正常预计值公式,确定了正常人D_LCO_(SB)的下限,探讨了其阳性判定标准,即D_LCO_(SB)以实测值/预计值<80％为异常。运用该标准对43例矽肺和弥漫性肺间质纤维化患者的阳性率与正常组阴性率进行了分析,发现上述判定标准的阳性检出率较高(90.70％),正常组假阳性率低于10％,适于临床应用。
In this paper, 120 cases of healthy adult (15 ~ 80 years old) were tested for lung CO diffusing capacity (D_LCO_ (SB)) with helium replaced with argon, and different gender , The mean value, standard deviation of different age groups, and the normal male and female predicted formula, the lower limit of D_LCO_ (SB) of normal people was determined, and the positive criterion was discussed, that is, D_LCO_ (SB) 80% is abnormal. Using the standard analysis of 43 cases of silicosis and diffuse pulmonary fibrosis in patients with positive rate and negative rate of the normal group were analyzed and found that the above criteria for the detection of the positive rate (90.70%), the normal group false positive rate At 10%, suitable for clinical applications.