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目的探讨联合使用玻璃酸钠和益赛普关节腔注射治疗类风湿关节炎的疗效。方法 64例类风湿关节炎患者随机分为两组:联合组30例,采用玻璃酸钠2 ml和益赛普25 mg进行膝关节腔内注射,以后单独皮下注射益赛普;对照组34例,膝关节腔内注入益赛普,以后单独皮下注射益赛普。结果两组患者随访6个月,联合组总有效率为93.3%,对照组总有效率为73.5%,两组疗效比较差异有统计学意义(P<0.05)。结论玻璃酸钠和益赛普联用与单用益赛普治疗类风湿关节炎均有疗效,但前者疗效更佳。
Objective To investigate the curative effect of combined use of sodium hyaluronate and Isocephala intra-articular injection in the treatment of rheumatoid arthritis. Methods Sixty-four patients with rheumatoid arthritis were randomly divided into two groups: 30 cases in combination group, intra-articular injection with 2 ml sodium hyaluronate and 25 mg prednisone followed by subcutaneous injection of ilexapril in control group, 34 cases in control group , Intra-articular injection of Yisipu, after a single subcutaneous injection of Yisipu. Results The two groups were followed up for 6 months. The total effective rate was 93.3% in the combined group and 73.5% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusions Both sodium hyaluronate and Isoprime combined with Yi-Sai Pu alone can treat rheumatoid arthritis, but the former is more effective.