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胃癌前病变主要是指胃粘膜非典型增生和大肠型肠化生。目前诊断主要依靠胃镜及活检,但当活检组织病理形态不典型,或形态异常较轻微时易造成漏诊。用胃癌单克隆抗体检测患者胃粘膜、胃液、血清及粪便等标本的肿瘤相关抗原,特异性强,敏感性高,可弥补常规病理诊断的不足,为临床确诊提供依据。
Precancerous lesions mainly refer to dysplasia of the gastric mucosa and intestinal metaplasia of the large intestine. At present, the diagnosis mainly relies on gastroscopy and biopsy, but when the pathological morphology of the biopsy is not typical, or the morphological abnormality is relatively mild, misdiagnosis may be caused. Detection of tumor-associated antigens in gastric mucosa, gastric juice, serum and feces samples with gastric cancer monoclonal antibodies has strong specificity and high sensitivity, which can compensate for the lack of routine pathological diagnosis and provide evidence for clinical diagnosis.