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心脏功能受心脏搏动的节律及幅度、心肌收缩力、主动脉压、周围血管阻力、植物神经及内分泌系统等多种因素相互作用的影响。有文献报道,丹参具有扩张血管、降低血压及抗菌怍用,常用于治疗冠心病、心肌梗塞等。丹参水提取物具有改善肾血流的怍用。活性成分除萘醌衍生物外,还分离出紫草酸镁盐及活性作用较低些的其它类似物。基于心脏不断重复地收缩和舒张以将血泵入周围组织,本文就咖啡酸类似物影响心输出量的两个主要因素——心脏搏动的节律和幅度进行了观察。试验用药咖啡酸类似物从丹参根中提取,lkg丹参水提取两次,过滤浓缩并进行柱层析,用水洗提后再用50％的甲醇洗提产
Cardiac function is affected by heart rhythm and amplitude of heart beat, myocardial contractility, aortic pressure, peripheral vascular resistance, autonomic nerve and endocrine system and other factors. It has been reported in the literature that danshen has the function of dilating blood vessels, lowering blood pressure and anti-bacterial, and is commonly used in the treatment of coronary heart disease and myocardial infarction. Salvia water extract has the use of improving renal blood flow. The active ingredient, in addition to the naphthoquinone derivatives, also isolated the magnesium lithospermate and other analogues with lower activity. Based on the repeated contraction and relaxation of the heart to pump blood into the surrounding tissue, the rhythm and magnitude of cardiac beat, the two major determinants of cardiac output of caffeic acid analogues, were observed. Experimental drug caffeic acid analogues extracted from Salvia roots, lkg Salvia water extraction twice, filtered and concentrated by column chromatography, washed with water and then 50% methanol washes