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目的观察持续与间歇口服盐酸特比萘芬片治疗甲癣临床效果。方法 125例甲癣患者随机分为A组(65例)、B组(60例),A组饭后口服盐酸特比萘芬片250 mg,1次/d,连服10 d,10 d,为1个疗程,共服3个疗程。B组饭后口服盐酸特比萘芬片250 mg,1次/d,连服2个月。结果经过2个月及4个月临床观察,A组与B组的总有效率、真菌镜检转阴率比较,差异无统计学意义(P>0.05)。结论持续与间歇口服盐酸特比萘芬片治疗甲癣临床效果无差别。但患者依从性好,且节省费用。
Objective To observe the clinical effects of continuous and intermittent oral terbinafine hydrochloride tablets in the treatment of onychomycosis. Methods A total of 125 patients with onychomycosis were randomly divided into group A (n = 65) and group B (n = 60). Group A was treated with terbinafine hydrochloride 250 mg once daily for 10 d, For a course of treatment, a total of 3 courses. B group after oral terbinafine hydrochloride tablets 250 mg, 1 / d, and even served 2 months. Results After 2 months and 4 months of clinical observation, the total effective rate of group A and B and the negative rate of fungal microscopy showed no significant difference (P> 0.05). Conclusion Continuous and intermittent oral terbinafine hydrochloride tablets for the treatment of onychomycosis no difference in clinical efficacy. But patient compliance is good and saves money.