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p16和PTEN均为抑癌基因,其表达均与许多肿瘤的发生、侵袭和预后密切相关。本研究采用免疫组织化学技术,探讨上述两种基因蛋白表达与大肠癌临床预后性指标的关系,以及两基因蛋白表达之间的相关性,为判断肿瘤预后提供参考指标。1资料和方法1.1临床资料:1998年2月~1999年4月我院普
Both p16 and PTEN are tumor suppressor genes whose expressions are closely related to the occurrence, invasion and prognosis of many tumors. In this study, immunohistochemistry was used to investigate the relationship between the expression of the above two genes and clinical prognostic indicators of colorectal cancer, as well as the correlation between the expression of the two genes in order to provide a reference index for judging the prognosis of the tumor. 1 Materials and Methods 1.1 Clinical data: February 1998 ~ April 1999 our hospital general