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目的研究ＣＳ２接触浓度与肾功能损伤的关系。方法对车间空气浓度、接触工龄及１８０名接触二硫化碳（ＣＳ２）作业工人和９０名同厂不接触ＣＳ２工人（对照组）尿蛋白值进行分析。结果ＣＳ２接触工人尿β２微球蛋白（β２ＭＧ）和白蛋白（ＡＬＢ）含量较对照组显著增高，且随ＣＳ２接触浓度增高、工龄延长而升高明显。结论长期接触一定浓度ＣＳ２可引起工人肾小管和肾小球的混合性损伤；β２ＭＧ和ＡＬＢ可作为慢性ＣＳ２肾损伤的早期监测指标。
Objective To study the relationship between CS2 exposure and renal dysfunction. Methods Urine protein values were analyzed in the shop for air concentration, exposure time, and exposure to 180 workers exposed to carbon disulfide (CS2) and 90 workers without CS2 (control group). Results The urinary β2microglobulin (β2MG) and albumin (ALB) levels of workers exposed to CS2 were significantly higher than those of the control group, and increased with CS2 exposure and prolonged service life. Conclusion Long-term exposure to a certain concentration of CS2 can cause mixed injury of renal tubules and glomeruli in workers. Β2-MG and ALB can be used as early monitoring indicators of chronic CS2 renal injury.