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目的:探讨吸入物变应原过筛试验(Phadiatop)结合皮肤点刺试验在变应性鼻炎诊断和治疗中的应用价值。方法:对100例临床表现疑似为变应性鼻炎的患者(变应性鼻炎组)和50例非变应性鼻炎患者(非变应性鼻炎组)进行Phadiatop检测,同时采用20种常见变应原作皮肤点刺试验,并进行对比分析。结果:变应性鼻炎组中Phadiatop检测、血清总IgE(TIgE)检测及点刺试验的阳性率分别为72.0%、38.0%及65.0%;非变应性鼻炎组中Phadiatop检测、血清TIgE检测及点刺试验的阳性率分别为40.0%、26.0%及8.0%。变应性鼻炎组中Phadiatop检测和点刺试验阳性符合率为92.3%(60/65),阴性符合率为80.0%(16/20),与TIgE检测的阳性符合率为47.7%(31/65),阴性符合率为85.0%(17/20)。结论:在变应性鼻炎的筛选诊断中Phadiatop检测的灵敏度高于TIgE检测,前者更具价值;皮肤点刺试验特异性高,有助于确定变应原,为治疗提供依据。
Objective: To investigate the value of Phadiatop combined with skin prick test in the diagnosis and treatment of allergic rhinitis. Methods: Phadiatop was detected in 100 patients with allergic rhinitis (allergic rhinitis) and 50 patients with non-allergic rhinitis (non-allergic rhinitis), and 20 common allergic rhinitis The original skin prick test, and comparative analysis. Results: The positive rates of Phadiatop, TIgE and prick test in allergic rhinitis group were 72.0%, 38.0% and 65.0%, respectively. Phadiatop and TIgE in non-allergic rhinitis The positive rates of prick tests were 40.0%, 26.0% and 8.0% respectively. The positive coincidence rate of phadiatop test and prick test in allergic rhinitis group was 92.3% (60/65), the negative coincidence rate was 80.0% (16/20), and the positive coincidence rate with TIgE test was 47.7% (31/65 ), Negative coincidence rate was 85.0% (17/20). Conclusion: The sensitivity of Phadiatop detection in allergic rhinitis screening test is higher than that of TIgE detection, the former is more valuable; the skin prick test is highly specific, which helps to determine the allergen and provide the basis for treatment.