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目的:探讨应用腔内超声消融结合介入技术治疗下肢深静脉血栓形成的效果;方法:回顾性分析121例下肢深静脉血栓形成患者应用超声消融结合介入技术治疗与溶栓治疗的临床资料;结果:超声消融组68例均超声消融成功,术中配合介入治疗,死亡2例,急性肾功能衰竭1例,切口淋巴漏14例,66例术后症状体征均消失,随访56例(1~5年)。溶栓治疗组53例治疗后症状消失或明显减轻,随访38例(1~5年)。二组比较,超声消融治疗组住院时间短(t,8.950;P0.0000),1-5年症状复发率低(t1a3.129P1a0.0140;t2a2.940P2a0.0187;t3a3.635P3a0.0066;t4a3.311P4a0.0107;t5a0.885P5a0.4019)。结论:与药物溶栓方法相比,腔内超声消融治疗下肢深静脉血栓形成,效果更快捷和显著,但需配合其它介入技术腔内治疗,并注意预防并发症的发生。
Objective: To explore the application of intra-uterine ultrasound ablation combined with interventional techniques for the treatment of deep venous thrombosis in lower extremities.Methods: The clinical data of 121 patients with deep venous thrombosis of lower extremities treated with ultrasound ablation combined with interventional therapy and thrombolysis were retrospectively analyzed.Results: Ultrasound ablation group 68 cases were successful in the ablation, intraoperative interventional therapy, 2 patients died of acute renal failure in 1 case, incision lymph leak in 14 cases, 66 cases of postoperative symptoms and signs disappeared, followed up 56 cases (1 to 5 years ). Fifty-three patients in the thrombolysis group disappeared or were relieved significantly after treatment, 38 cases were followed up (1-5 years). In the two groups, the hospitalization time was shorter in the ultrasound ablation group (t, 8.950; P <0.001), and the recurrence rate was lower in the first 1-5 years (t1a3.129P1a0.0140; t2a2.940P2a0.0187; t3a3.635P3a0.0066; t4a3). 311P4a0.0107; t5a0.885P5a0.4019). Conclusion: Compared with the drug thrombolysis method, intracavitary ultrasound ablation of deep venous thrombosis of lower extremities, the effect is more efficient and significant, but with the interventional treatment of other endovascular techniques, and pay attention to the prevention of complications.