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目的探讨小睑裂综合征对视觉发育的影响及分期手术治疗先天性小睑裂综合征的临床疗效。设计回顾性分析。研究对象北京同仁医院2005年6月至2009年5月间住院治疗的小睑裂综合征患者51例(102眼)。方法每例患者作屈光及眼科检查,详细询问家族史,全部病例均行分期内眦开大术或(和)外眦开大术及上睑下垂矫正术。主要指标屈光检查结果,术前术后睑裂长度、宽度及内眦间距。结果13例有家族史,46眼有完整的散瞳验光结果,其中27例存在不同程度的弱视,12例伴不同程度的屈光不正,4例斜视,1例斜视伴眼球震颤。病例术后随访时间8个月～4年,获得满意外观。结论先天性小睑裂综合征患者弱视及屈光不正发生率较高,需要早期手术治疗及视觉干预。分期手术治疗可获得满意效果,有效改善外观。
Objective To investigate the effect of palpebral fissure syndrome on visual development and the clinical efficacy of staged surgery for congenital palpebral fissure syndrome. Design retrospective analysis. The study included 51 patients (102 eyes) with palpebral fissure syndrome admitted to Beijing Tongren Hospital from June 2005 to May 2009. Methods Each patient was examined with refractive and ophthalmologic examinations. Family history was asked in detail. All patients underwent open surgery (or) and open surgery and blepharoptosis surgery in all cases. The main indicators of refractive examination results, preoperative and postoperative palpebral fissure length, width and internal 眦 spacing. Results There were 13 family history and 46 eyes had complete mydriasis optometry results. There were 27 cases of amblyopia with varying degrees, 12 cases with varying degrees of refractive error, 4 cases of strabismus and 1 case of strabismus with nystagmus. The patients were followed up for 8 months to 4 years, obtaining a satisfactory appearance. Conclusions Patients with congenital palpebral fissure syndrome have a higher incidence of amblyopia and refractive errors and require early surgical treatment and visual intervention. Staging surgery can be satisfied with the results, effectively improve the appearance.